Saturday, June 20, 2015

Depression : Is it seratonin or SSRI deficiency? (Part 1)

Have you ever feel depressed or anxious from time to time? Have you ever been diagnosed with depression or any mental disorders? As more people are being diagnosed with depression, it is the world’s second biggest cause of disability, according to a study by researchers from The University of Queensland. If you are one of victims and seeking for alternative solutions or knowing more about this condition, this topic series may well be your life safer.

As experts predicted that this condition will likely be the number one cause of disability globally in years to come, the statistics are not looking good, in terms of conventional diagnosis and treatment, and many more people are suffering from this illness, as of present time and future. Is there one approach or treatment for every different individual? It is often easy to apply the same 'one size fits all' approach to every patient when he or she walks into the doctor's clinic. But, many of us now realized that in terms of disease diagnosis and treatment, conventional paradigm of medical drugs may well be a huge failure, accompanied with side effects which cause more problems (side effects) to the body then attempting to fix anything.

In a similar analogy, conventional approach for patients who suffer from fever to go on paracetamol or aspirin, or in the field of dietary, or cancer patients undergo chemotherapy/radiation for a hopeful treatment. Most authors of diet books will claim that their own diet protocol is healthy and suit everyone else and there is no difference between many fitness professionals who proudly endorse their own workout DVDs and claim to be the best weight loss program ever. 

We humans, are biochemical individuals, and with our own unique physiological adaptation and built, genes are being expressed constantly, be it from our diet, lifestyle or environmental stressors. Thus, 'one size fits all' approach by treating all depressed patients with SSRI drugs seemed to be an easy puzzle to solve. Does it really work? How effective is SSRI drugs? 

In conventional medicine, SSRI (anti-depressant) drugs are prescribed to patients primarily diagnosed with depression or showed any symptoms of anxiety or similar mental disorders. It is primarily based on a neurotransmitter model. The idea is to recycle and use the available seratonin neurotransmitters in the brain for a longer period of time. However, this approach failed to assess other factors or possibilities for triggering or increase the likelihood of depression in an individual. As for some patients, it may worked for a short period, but the root cause was never investigated, and in most cases, the condition worsen and new sets of symptoms may appear overtime. Same apply for most alternative treatments, where patients are given Tryptophan or 5-HTP supplements to treat depression. For most people, it may improve the condition and make that individual feels better, but still, the underlying cause is yet to be identified, although this approach is a natural and less side effects. 

Some of the possible factors we will learn in this topic discussion includes gut to brain axis, co-factors function of primary neurotransmitters such as serotonin and dopamine, the role of chronic inflammation in depression, toxins and diet as one of the culprits in making an individual become depressed, and also certain genes which can deplete one's serotonin faster then others or block production of neurotransmitters. If you have read my earlier posts on Brain Chemicals, this would be an extension and updated version of brain health and depression.

As statistics have shown that up to 60% of total patients have unsuccessful results or effect from anti-depressant drugs during 1st prescription from doctors. For some, they may feel better but it is not a long term fix and will never address the root cause of the problem. The general idea of anti-depressant drugs is meant to use and recycle the available serotonin in the brain longer, but what if certain people naturally have low serotonin production? How many conventional doctors actually dig deeper and ask the question why this is happening? Or is it solely serotonin deficiency?

There are so many variables and factors which could cause depression. For the ancient tribes or population, they believed that depression is a gift from god, a visitation of guardian angel to look at your life, what is wrong with your life. Why are you depressed? How are you living your life? Going for a pill prescribed by a doctor sounds so simple and aiming for a quick fix, and that merely mask the symptoms of what is actually going on physiologically and psychologically.

Stay tuned. 













Reference/Journal: 
http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1001547


Monday, June 8, 2015

Vitamin E: What you need to know

Supplements are selling better then ever, in pharmacies, health food stores and online supplement websites too. Many of us, are consistently relying on supplements to support our health and body and spending big bucks monthly on some of the so called 'supplements'. The questions is, how much do you know about the quality, ingredients and effectiveness of these supplements? Do you know that some of these supplements may do more harm then good? 

Today, I want to discuss about Vitamin E supplement. Yes, the ones which are widely sold and available in almost all pharmacies and health stores. As few have good knowledge about nutrition and how the body works, we tend to be influenced by commercials and so called health experts, and rely on paying for supplements hoping to slow down the decline of our health, or tackle some of our health symptoms along the way. But, how many of us, really know that the almost all of the Vitamin E products sold in the market are synthetic, partial and low quality? 

Many clinical trials unfortunately use synthetic (man-made) vitamin E on participants, which do not confer healing benefits. Would you expect it to? They use a fraction of the whole molecule of vitamin E called “ALPHA” tocopherol, and for this reason their results are bad. Well of course!! What do you think happens to a human being when you cheat them out of 7 other parts of vitamin E? Think about it, seriously, take  a moment to think. How far can you possibly get building that puzzle with one piece? I would say, not very. 

What do you think happens to humans when you give them lab-created compounds that do not match what naturally occurs in nature? Vitamin E is awesome, and it’s just as awesome as vitamin A, vitamin D and other essential nutrients that your body requires for optimal health. Vitamin E is a fat-soluble nutrient so it feeds and nourishes fatty tissue, especially your heart, pancreas, liver and brain. Your brain loves E, especially if you’ve had a TBI (traumatic brain injury).

Vitamin E is like super fuel for your brain but if you take a low-quality form. Sadly, there’s a lot of junk out there. Unnecessary fillers, binders, colors, excipients, even the isomer of your E.  Same with other nutrients such as ketones (from coconut or palm oil), choline, curcumin, and healthy fats.  Now, check this out. Do you see “dl- alpha tocopherol” on your label? All synthetic forms of vitamin E are labeled with a dl- prefix. The synthetic form is generally 50% less bio-available to human body. Natural E has the d- prefix only (not dl) and is easily recognized by your cells.

Natural E, as it occurs in nature is part of a family of 8 compounds, alpha tocopherol is just one of them! So when you take conventional E supplements you are getting one-eighth of what you should be getting. Worse than taking one-eighth of pure vitamin E, when you take poor quality supplements of E, you are flooding your body with one isomer, and thus depleting the other 8 forms of E. Eventually, it will get tilted out of balance. 

Now, let's talk a bit about tocotrienols. This is the less talked about puzzle piece of natural E. Collectively speaking, the tocotrienols (all four of them)  have very strong antioxidant activity. Tocotrienols are 50 to 70 times more potent than tocopherols and penetrate deeper into fatty tissues like your brain, and liver. Tocotrienols are found in mostly in palm oil, soybean oil and rice bran oil with trace amounts in wheat, rye and barley. Please do take note on the contamination of gluten in these products.  Other sources of tocotrienols include oats, grapefruit seed oil, nuts especially walnuts and hazelnuts, high quality olive oil, flax seed oil, sunflower oil. Again, do take note on the vegetables oils which may do more harm then good to the body due to oxidized fats (trans fat) and other chemical compounds during processing. 

Meanwhile, did you know “gamma” tocotrienol protects mammary tissue? That is huge news to women who live in fear of breast cancer or those who have recovered. There is also another brand new study on asthma, comparing tocopherols with tocotrienols, where the researchers come right out and said, “Clinical trials of tocopherol supplementation to assess the impact of antioxidant activity in asthma have yielded equivocal results. Tocotrienol exhibits greater antioxidant activity than tocopherol in several biological phenomena in vivo and in vitro.”  The favorable results were just published (May 2015) in Pulmonary Pharmacology and Therapeutics. I have included both studies in the links down below. 

There are many studies which showed positive results which tied to this awesome nutrient. It is crucial that our body assimilate sufficient amount of Vitamin E for bodily functions on daily basis. Diet and nutrition is crucial, and ensuring the gut health for optimum digestion and assimilation is the key prior to investing on any of these supplement products. Although today's post is about Vitamin E, but the message here is to be aware of the supplement products you buy in the market or any pharmacies. The end goal is still to focus on your diet and lifestyle factors especially stress levels. Chronic stress will depletes most of your anti-oxidants levels and neurotransmitters as well. And if you would to purchase any Vitamin E supplement, ensure it is non-synthetic and contains not only a single form. 


Complete Vitamin E:

alpha tocopherol
beta tocopherol
delta tocopherol
gamma tocopherol
alpha tocotrienol
beta tocotrienol
delta tocotrienol
gamma tocotrienol



Studies/references:
http://www.ncbi.nlm.nih.gov/pubmed/25956071
http://www.ncbi.nlm.nih.gov/pubmed/15792944







Wednesday, May 13, 2015

Statin Nation II - A documentary everyone MUST watch, if you are concern about heart disease and real cause

If you have watched Part 1 of Statin Nation, you will enjoy this documentary for sure. Statin Nation II reveals the truth about heart disease, and the culprits behind this silent killer, which have killed millions of people around the world. This second installment of the documentary explains and shows the viewers of the real cause of cardiovascular disease, interviewing top scientists, doctors and researchers all over the world.

In 1961, Ancel Keys adopted the idea of saturated fats causes heart disease. And in 1984, cholesterol was then to be blamed for heart disease as published by TIME magazine. Till now, in June 2014, TIME magazine admitted that we were wrong the whole time!  From 1961 to 2014, more then 50 years of flawed science and screwed up made by so called scientists or health professionals, we are now back to square one, where our ancestors ate lots of saturated fats and cholesterol and were super healthy.

As I have just received my copy of this documentary,  I have to say that it's brilliant, yet mind blowing. It's a documentary which you will want to watch it over and over again, and share it with your loved ones. 



Short clip of Professor Sultan from Statin Nation II


Video link: https://vimeo.com/ondemand/sn2/119674349



Short clip of Familial Hypercholesterolemia from Statin Nation II


https://vimeo.com/122587702






Sunday, April 26, 2015

Maintaining fitness of a lifetime, and better health - Overtraining & Adrenal Fatigue (Part 13)

Ironically, as I'm writing this final post about adrenal fatigue and stressors which affect our health and energy levels, I had to endure a stressful week myself. Being someone who is very conscious about my own body and soul, I was relieved a bad week in my workplace had passed, and lots of healing and restoration needed, as I'm trying to get back on track to balance out my autonomic nervous system. I just realized how some of my friends have to endure for years, working in a stressful job day in day out, even on weekends, these folks do not have peace of mind. Most of these people I know are either in high position managerial status or working in sales department. In today's post, I will try to blog with a mildly foggy brain (still recovering), about energy levels in relation to mitochondria and adrenal functions, as well as how blood sugar dsyregulation is vital to maintaining health and fitness.

Low energy cannot always be traced to low adrenal function per se. The fault, in fact, may lie at the very foundation of cellular energy, your mitochondria. These are the bean-shaped powerhouses within each cell that use oxygen to convert the energy in food to chemical energy in order to fuel the cell's activity. Therefore, any significant damage or alteration in mitochondrial function has the potential to greatly affect your energy levels.






Many forms of stress and/or toxic exposure can damage our mitochondria, not the least of which includes other damaged mitochondria. As mitochondria age in our cells, they become progressively inefficient and potentially toxic, and acute damage can trigger the permeabilization of mitochondrial membranes to initiate apoptosis or necrosis. Another major source of mitochondrial dysfunction is prescription and over-the-counter medications, which may explain many of their adverse effects. All classes of psychotropic drugs have been documented to damage mitochondria, as have statins, analgesics such as acetaminophen, and many others. 

Damage to mitochondria is now understood to play a role in the pathogenesis of a wide range of seemingly unrelated disorders such as schizophrenia, bipolar disorder, dementia, Alzheimer's, epilepsy, migraine headaches, strokes, neuropathic pain, Parkinson's disease, ataxia, transient ischemic attack, cardiomyopathy, coronary artery disease, chronic fatigue syndrome, fibromyalgia, diabetes, etc.

If your mitochondria are not working right, then you don't work right either. In fact, energy-intensive organs like the heart and the brain are especially dense with mitochondria which means they are especially vulnerable if the mitochondria are compromised. Mitochondrial respiration produces adenosine triphosphate, better known as ATP, a storehouse of chemical energy. However, the process also generates damaging free radical activity. 

Scientists recognize mitochondrial dysfunction as a key biomarker of aging. And researchers have recorded evidence of 50 percent more mitochondrial damage in the brain cells of humans over the age of seventy compared to middle-aged people. Mitochondrial dysfunction and death are now definitively linked to the development of virtually all killer diseases of aging, from Alzheimer's and type 2 diabetes to heart failure.

Consider for a moment that one of the characteristics of seemingly depressed adrenal function is a state of chronic fatigue. What we choose to eat for energy can make an enormous difference in terms of how our body regulates our physiological energy levels. When it comes to energy availability, we need to ask ourselves the following question: What are the two fuels the brain and body are able to make primary use of? The answer is glucose and fat. Dietary fat is eventually broken down into what are called ketones or ketone bodies. The body's principal ketone is beta-hydroxybutyrate, which is burned for fuel, along with free fatty acids (outside the brain).

I look at a carbohydrate-based diet and metabolism as keeping your metabolic woodstove going by using little more than kindling. Starchy foods like brown rice, beans, whole grains, and sweet potatoes, all effectively operate functionally like twigs on that metabolic fire. White potatoes, white rice, white bread, pasta, and cereal are more or less like crumpled paper thrown on that fire. Alcohol and sweetened beverages are like gasoline or lighter fluid.




Blood sugar fluctuations throughout the day on a carbohydrate-based diet. Fat burning keeps you in the solid, green zone. Are you sugar or fat burner?




All of us, even slender people, have a supply of fat on our bodies that could potentially keep us going for close to a month, though I wouldn't necessarily recommend it. But almost nobody stores more than a couple thousand calories of glycogen at any given time, at least not very efficiently. You can burn that off rather quickly, so it needs to be constantly replenished. 

And think about this. Who do you suppose might profit from you constantly having to replenish your energy levels with metabolic kindling? I would submit that a carbohydrate-based diet or metabolism is a better way to serve multinational corporate interests than it is to serve your own best health. Considering that all print, radio, and television media is presently owned and monopolized by no more than about five of these corporate interests, don't expect to hear about the virtues of what I am describing in the mainstream news anytime soon.


Which diet is the healthiest?
As we browse through any bookstore in diet section, we find ourselves pondering which diet book is really good or rated as the healthiest amongst all. Some of us may feel confuse as most books contradict each other and of course all authors claim that their diet protocols are the best and everyone should be follow what they proposed in the book.

The question is, is there one size fits all diet? From Paleo to Vegan, or Atkins to 20 bananas a day diet, which one will be crowned as the undisputed king of all diets? Well, sorry to burst your bubble, but there is no one size fits all diet. Each individual has his or her own metabolic type, different biochemical and physiological responses, and even different body type structurally. If there is really a single diet which is the most effective and healthiest, everyone would be symptom-free and achieve the best shape of their lives.

For instance, person A may do alright eating predominantly vegetables in a meal, but person B may feels sluggish and hungry after just an hour. In other case, you may be feeling great having eggs for breakfast, but I may be feeling foggy or excess mucus production after that. A particular food may benefit or do well in a person, but could turn out to be intolerant or sensitive, or even trigger a negative immune reaction for another person.

Bare in mind, we are not talking about conventional dietary guidance or wisdom such as calories in and out, but in order to find out if any form of eating plan or protocol suit you, you have to listen to your body, and eating in accordance to your own metabolic type and eliminate food intolerance and sensitivity too. Besides, having a lifestyle and diet which maintain a steady blood sugar level is extremely crucial. As for all my clients. I will have them keep track of their daily diet and lifestyle logbook updated from time to time for evaluation and fine tuning to achieve better results.


Short term goals or long term sustainable? Are you fit but sick?
As we all know, almost all of us want to have the body we came across in fitness magazines or Hollywood movies. From fitness models to celebrities or even some unknown figures we seen in the gyms, the surroundings have created a desire which made most of us focus on what is in front of the mirror, but forgotten about what is even more important. health.

From workaholic to fitness enthusiasts. how many of us really listen to our body? How many of us will put health ahead of fitness or the job which is slowly killing the soul and body? From 'I need to lose weight in 2 months in time for an occasion', to 'I need to have six pack abs within 6 months', all these goals are nothing but direct reflection of a concious state of mind, failing to align with the soul, the heart and falling off the holistic paradigm which usually turn out to be a sick but fit individual. In most cases, a good looking physical body masked by a crying misaligned mind and soul filled with pain, exhaustion and diseased-laden self.

Have you ever fall sick more then couple of days in a year? Are you regularly battling with symptoms such as constipation, diarheaa, sinus infections, bloating, gas, headaches, low energy levels, low libido, acid reflux. dry hair and skin, joints pain, etc? Many people who are obsessed about getting fit or building the body they always wanted, tend to lose track and derailed from what the body actually need to survive and achieving optimal health. You can't build a brick house with woods, remember?

From news we read to people we know, the so called fit people suffered from serious health problems and for some, drop dead at early age from heart failure. The question is. are you fit but sick?


I know I know...now what? 

From a humble person to an egoistic alpha male personality, decision is always up to you in the end to make your choices. My goal in this post is to provide you the list of 'in a nutshell' self evaluation and action items to do, and the rest is within your control. Remember, knowledge is not power, but applied knowledge is POWER.


- In terms of exercise, workout is only part of the entire equation. If you are a stressed out individual or has a stressful job or relationship (or any form of mental, emotional or nutritional stress), the last thing you want to do is to bang yourself out day after day in the gym for a long period of time. Integrating specific work-in exercises will help to balance out the body-mind-soul and giving the adrenals some rest and enable better results, repair and growth.

- How would I know if I'm a sick and suffering from poor health? There are some key biomarker tests to run to give yourself a baseline data of telling you your state of health. But not everyone can get hold of functional lab tests such as Intestinal Muscosal Barrier and Functional Adrenal Stress profile. Another test I would highly recommend is Cyrex Array 5 Multiple Autoimmune Reactivity Screen. And for anyone who is concern about risk of heart disease, running homocysteine and CRP high sensitivity tests are valid and important biomarkers. You can get both these tests done in conventional hospitals and certain clinics.

http://www.cyrexlabs.com/CyrexTestsArrays/tabid/136/Default.aspx 
http://biohealthlab.com/


- Breathing. Yes, everyone is lacking this crucial foundation of health and autonomic regulation. The most important fundamental regulatory mechanism for digestion, detoxification and all other survival functions in the body. The ones who are sympathetic dominance (stressed out), tend to have shallow breathing and typically more then 12 breathes per minute.

- Measure your blood sugar level after every meal (around 40-45 minutes after completion of a meal). Of course you don't have to measure it daily for the entire year, but start off with maybe 14 days to obtain a pattern of how your typical diet affect blood sugar levels. It is extremely important to find out if your are insulin resistance, or suffering from poor blood sugar dsyregulation, which is a recipe for diabetes and cancer. Remember, cancer cells feed on sugars.

- In conjunction with blood sugar measurement, one can perform pulse test after every meal. Do a 60 secs pulse test after about 20-30 mins upon ingestion of any foods or meal. Compare it with your average pulse, anything more then 4 pulses is a sign of negative immune reaction against that particular food. Do a daily logbook recording of your own data, for both blood glucose measurement and pulse testing.

- Have a private alone time by yourself. Reserve at least 20-30 mins each day, alone in a room or a place where there is no disturbance or any communication of sorts. An ideal scenario would be during night time in a dark quiet room, listen to your soul and have a moment of peace for the day. No mobile phone, no TV, no kids barging in the room, no nothing.










Friday, April 3, 2015

Maintaining fitness of a lifetime, and better health - Overtraining & Adrenal Fatigue (Part 12)

Are you sugar or fat burner? Have you ever thought which fuel your body utilize to burn day in day out? As most people are eating according to their emotions and cravings, many of us are eating with accordance of USDA food pyramid, but for some, it's a diet protocol eating plan. The question is, how would you know if your body is running on fats or sugars as fuel?

As I've just recently returned from an awesome Holistic Lifestyle Coach certification, I recalled my mentor Jo Rushton was discussing about how most people are living on sugars, caffeine and other stimulants day in day out, just to get their energy levels going. Apart from burning out the adrenals from these stimulants, you are turning your body into a 'sugar-burner', instead of fat burning machine. Most people are walking un-rested, tired and wired. As there are more insulin-resistant homo-sapiens then ever before on this planet, most of us are stimulants dependency, from world most popular beverage coffee to sugar coated foods, we are indeed WIRED!

With sky high cortisol stress hormone pouring out day and night, the adrenals are just being stressed to the limit, and disaster is awaiting (could be years or decades). I'm talking about autoimmunity, Addison's disease, poor sex life and reproductive health, sluggish thyroid and a long list of other problems.

There are several reasons why your cortisol levels may be floundering. It can take a lot of detective work to figure it out, but there is always an underlying answer and most of the time there is plenty that you can do to improve things naturally. Most things people do to self-medicate aren't helpful in the long run. For example, got a Red Bull habit? It's time to break your dependency on that trashy stimulant. Love bungee jumping or sky diving? You may have to forgo the adrenaline rush if you want to save your adrenals. Got a sweet tooth? There are healthier and more sustainable ways of boosting your energy and alertness. Diets high in sugars and starches, and poor and irregular eating habits put you on a roller-coaster ride of constantly using your adrenals to manage your blood sugar. And that is a surefire way of adding unnecessary stress to your own personal stress hormone factories.

The first big challenge is to pinpoint whether the adrenal glands are truly at fault or if there is some other culprit. For instance, what looks or feels like adrenal burnout can also be potentially related to one or more of these conditions or situations:



  • Free radical processes 
  • Malignancy (cancer) 
  • Pituitary gland hypofunction (manifesting here as low ACTH). This tends to appear on blood chemistry tests as low TSH coupled with low T4 
  • Other secondary hypothyroidism related to low T4 or elevated thyroid binding globulin (TBG) found occurring at times with extreme chronic stress. 
  • Primary hypothyroidism (with or without autoimmunity) 
  • Abrupt withdrawal from long-term steroid use leading to down regulation of cortisol receptors 
  • Iron deficiency 
  • Insufficient cholesterol perhaps due to taking a statin or eating a very low-cholesterol or vegan diet 
  • Other nutritional deficiencies, such as of certain B vitamins, fat soluble nutrients, or essential fatty acids 
  • Malabsorption (digestive disorders, leaky gut, etc.) 
  • Autoimmune disorders in general 
  • Chronic or extreme, acute stress that either depletes or exhausts the body's steroid hormone stores 
  • Blood sugar dysregulation! A diet high in sugar and starch or poor and irregular eating habits can lead to a roller-coaster ride when you are constantly using your adrenals to manage your blood sugar. Adrenals were not designed to manage your blood sugar levels 24-7. 
  • Too frequent stimulation from substances like coffee and nicotine, excessive exercise, or risky experiences that give you a big adrenaline rush 
  • Burning the candle at both ends.


Remember that adrenal hormones are all about survival. The push to survive takes precedence over absolutely everything else, including producing sex hormones and their precursor, immune-enhancing DHEA. Think about it. If a saber-toothed tiger is chasing you, how much priority are sex hormones to your survival in that moment? And if you are metaphorically being chased by saber-toothed tigers 24-7, how are your sex hormones (not to mention your sex life) going to be after a while? Not exactly the best prelude to date night.

The phenomenon called pregnenolone steal refers to the body's ability to shunt steroidal hormone production away from sex hormones, leading to big problems, uncomfortable symptoms of androgen deficiencies for men, and hormone dysregulation and uncomfortable PMS and menopausal symptoms for women. If you had read my previous posts, I've explained about PREGNENOLONE STEAL. 

The pregnenolone steal occurs when the body virtually steal the pregnenolone needed for the production of other steroidal hormones in an attempt to keep pace with the demand for more cortisol during periods of stress. Cortisol is a critical survival hormone and (as previously pointed out) the need for survival always trumps everything else. Women are frequently prescribed hormonal creams in an attempt to counter this underlying trend and ameliorate uncomfortable symptoms. But without addressing the foundational problem and only putting a Band-Aid over the symptoms, all too frequently the problem only deepens. The only true solution lies in identifying and addressing the underlying source of stress driving the need for cortisol. The complexity of the interrelationships between steroidal and other hormones in the body should never be ignored and cannot ultimately be overruled by medications.

It's certainly not that your body is too stupid to make enough testosterone or estrogen or progesterone. Your body is slowing its production of certain hormones for a reason, and addressing it is the only way to restore healthy hormone levels. Your body will eventually have its way and persist in its efforts to depress your hormone levels, even if you feel some short-term relief from hormone creams and other bio-identical supplements. There is a place for them and a time for them, but, in my opinion, they are greatly overused.

Anyone remember President John F. Kennedy? He is one of the most famous sufferer of a form of adrenal autoimmunity called Addison's disease. Adrenal autoimmunity is extremely common today, but Addison's disease is only rarely if ever diagnosed. Why is this? 

According to the current medical standards of diagnosis, you are unlikely to be diagnosed with Addison's disease until you have a minimum of 90 percent of your adrenal tissue already destroyed. But by that point you have already been producing adrenal antibodies for years if possibly even decades! If your tissue destruction is only half of this, maybe just 45 percent, I promise that you will notice it in every part of the way you feel and how you function in your life. However, you are unlikely to get answers from your family physician or even an endocrinologist, and you are not going to know what's wrong with you unless you have specialized tests designed to look for the early signs of this.

So you could be suffering an autoimmune adrenal process (and be symptomatic) for years and years without actually being diagnosed with Addison's disease. In the meantime, you are going to be calling it chronic fatigue or adrenal burnout and wondering why all the adrenal supplements you are taking don't work. Before I sign off this post, let me present to you some of the list of symptoms of adrenal autoimmunity.



SYMPTOMS OF ADRENAL AUTOIMMUNITY

Some of these symptoms are due to depressed levels of aldosterone and other corticosteroids, which is why these complaints are also commonly characteristic of adrenal burnout:


  • Chronic physical and mental fatigue 
  • Unexplained low blood sugar symptoms and carbohydrate cravings 
  • Salt cravings 
  • Craving for stimulants, such as caffeine and nicotine 
  • Chronic low blood pressure 
  • Weakness 
  • Stress intolerance 
  • Weight issues 
  • Dizziness, especially when you stand from sitting 
  • Muscle or joint pain, or both 
  • Gastrointestinal disturbances or abdominal discomfort, or both 
  • Anxiety 
  • Depression 
  • Increased skin pigmentation over time 



Stay tuned for final post of this entire topic.

Tuesday, March 17, 2015

Maintaining fitness of a lifetime, and better health - Overtraining & Adrenal Fatigue (Part 11)

This person is depressed, always tired, often anxious, craves alcohol almost as much as coffee. This person also craves carbohydrates and always seems to be snacking. This person may simply try to live on his or her artificial nervous energy and caffeine boosters throughout the day instead, punctuated by the occasional bagel or donut and skipping real, regular meals. This person has what practitioners of mainstream natural medicine call adrenal exhaustion or burned-out adrenals.

It just so happens that this particular person also has food sensitivities plus parasitic and chronic viral infections. He or she has a lot of chronic personal stress, is drinking too much, and isn't getting enough rest. He or she is commonly awakens in the middle of the night with what feels like a surge of adrenaline, which may relate to her body's way of compensating for insufficient cortisol at these times. The question is, does this sound familiar to what you are experiencing? 

As high cortisol production has been getting more publicity and primary discussion, but how about if a person is running low on cortisol production? What if that someone is losing ability to produce cortisol on daily basis? What will actually happen to that individual? What would his or her symptoms be? 

There are several possible causes of this person's low cortisol level. For starters, and from a brain-based perspective, her food sensitivities and infections are generating inflammatory cytokines, which adversely alter the paraventricular nuclear (PVN) cells of her hypothalamus and are likely effectively dampening their output. It is known that certain inflammatory cytokines adversely modulate brain neurotransmitters and the activity of the hypothalamic-pituitary-adrenal axis. These conditions, and the other causes of her low cortisol problem, need to be addressed individually and not with a bunch of adrenal supplements. 

That said, when cortisol is chronically depressed, there is a particular supplement called licorice root extract (not the candy!), that can help preserve the half-life of cortisol and help extend its activity. It doesn't affect actual cortisol production but rather helps maintain what little cortisol happens to be available and allows your body to use it more effectively. 

Now, let's pause for a moment and take a look at some of the symptoms of chronically low cortisol.


COMMON SYMPTOMS OF CHRONICALLY LOW CORTISOL/ADRENAL INSUFFICIENCY

  • Chronic fatigue 
  • Decreased tolerance to cold or stress 
  • Poor circulation 
  • Low blood sugar symptoms (hypoglycemia). This is NOT a dietary sugar or starch deficiency! 
  • Craving caffeine, sugar, and stimulants 
  • Carb (and/or alcohol) cravings in general 
  • Low blood pressure 
  • Apathy or depression 
  • Poor libido 
  • Poor stamina 
  • Joint aches and pains 
  • Muscle weakness 
  • Salt cravings 
  • Needing excessive amounts of sleep and/or awakening to anxiety-provoking adrenaline surges in the middle of the night 
  • Low resistance to infection 
  • Having a possibly subnormal basal body temperature 
  • If adrenal deficiency is coupled with a loss of DHEA production, hair loss in pubic and underarm areas can occur. 

You know the symptoms, and you will be asking questions, "What's my next step? How should I deal with it?". Let's look at a list of considerations to tackle low cortisol production, but each individual may vary in terms of effectiveness and time frame of improvement.



SO WHAT SHOULD YOU DO IF YOUR CORTISOL IS TOO LOW?

  • First, you need to determine and address all potential sources of inflammation or infection. 
  • Have your ferritin levels tested. Ferritin is the best measure of your iron levels, and you need iron to produce cortisol. Large amounts of an iron-containing protein are present in the adrenal cortex, and are involved in the synthesis of corticosterone. If your iron is low, you will also tend to have a low cortisol level and what appears to be adrenal fatigue. Also, the thyroid and adrenal glands tend to work best when your ferritin level is somewhere between 80-110 ng/mL. If it gets much higher, I start worrying about iron overload. If it is much lower than about 40, you may have chronic anemia. Women will routinely complain of hair loss when their ferritin levels are between 40-60 ng/mL, fatigue and light-headedness occur when between 20-40 ng/mL, and a level of 20 ng/mL or lower can manifest in heart arrhythmias, breathlessness, irritability, nerve pain, or restless legs syndrome, to name just a few symptoms. 
  • Take licorice extract in the morning and early afternoon (if needed) to make the most of the cortisol you have. Use it with caution if you have an issue with high blood pressure. Don't use it late in the afternoon as it can interfere with your sleep. Follow the recommendations on the label to start, then increase the dose as needed for feelings of improvement. 
  • Control your blood sugar or switch to a fat-based diet. 
  • Take turmeric/curcuminoid supplements to help dampen potential inflammation/neuro-inflammation. 
  • Evaluate symptoms for neurotransmitter deficiencies 
  • Taking certain specific amino acid precursors together with needed accessory nutrients may help at least temporarily relieve your symptoms. This can at least make you more comfortable while you are finding the cause of your low cortisol or otherwise depressed neurotransmitter levels. 
  • Get a proper evaluation of your pituitary health through a qualified health care provider. Severely impaired ability by your pituitary to produce ACTH is most commonly caused by a tumor, though simple prolonged chronic stress may also lend itself to diminished secretion. Evidence for this can sometimes show in depressed TSH plus depressed total serum T4 (thyroid hormone) levels. See your doctor for more thorough testing. 
  • If your depressed cortisol levels are related to adrenal autoimmunity, know that some people have found supplementing with high quality neonatal bovine adrenal glandular supplements significantly helpful. 

Stay tuned for next post. 


Wednesday, March 4, 2015

BOUGHT - The truth about vaccines, Pharmaceuticals and GMOs

Have you always been curious and wanting to know the truth about vaccines and the science and politics behind it? Or are you still having doubt after even reading the book titled 'Bad Pharma' by Dr. Ben Goldacre? Do you want to know more about GMOs foods and what it can do to our body and health? Then watch this very important documentary BOUGHT, if you genuinely want to protect your kids and find out a whole load of truth bombs about vaccines, pharmaceutical drugs and GMOs foods.

You can watch the entire movie for FREE until 6th March 2015, but I still recommend everyone (especially parents) to watch this documentary even if you have to purchase the DVD. Remember, the physiological and muscoloskeletal growth of a child, or behavioral state of your son or daughter, or perhaps the risk of recurrence infections and diseases, is within the control and final decision are made by the parents or guardians. The innocent child or kid, will not know which foods are bad or if pharmaceutical drugs will rob off minerals and nutrients from the body or damage gut health and a long list of other side effects. 


Website: www.boughtmovie.com