Sunday, December 1, 2013

Gluten Ataxia : Commonly misdiagnosed autoimmune-mediated disorder

Recently, while I was reading some of the medical journals which relates to autoimmune disease and gluten, I came across a couple of very interesting articles about a autoimmune disorder called Gluten Ataxia. I'm not an expert of this field nor this condition, but I will share what I found out and some of the important information which more people should be aware of, especially gluten.

Almost everyone is addicted to gluten and wheat, and some even thought that this is 'staff of life'. The western can't live without wheat-based foods and gluten has wreaked havoc in their health and majority of people are not aware of the damage caused by gluten. Gluten ataxia, is one of the more commonly misdiagnosed condition/symptom by most doctors. According to one of the studies published, gluten ataxia is an immune-mediated disease triggered by the ingestion of gluten in genetically susceptible individuals. It is a common manifestation of sensitivity to gluten.

As I've read through a few published journals from two different universities, below are my 'in-a-nutshell' summary and explanation for this gluten related disorders. Whoever are suffering from below symptoms and your doctors are unable to help you, you may find below information helpful, in some ways. Good luck.


Symptoms of gluten ataxia : 
- Loss of balance, coordination, slurring of speech, tendency to fall, double vision, body inability to control muscular coordination. All these symptoms could be intermittent occurrence, depending on the severity of the condition. 

Who is in risk of developing gluten ataxia?
Ataxia can be caused by genetics, multiple system atrophy, excessive alcohol intake and gluten sensitivity. People with genetic markers of DQ1, DQ2 ad DQ8 are seen in ataxia patients.

What to avoid in diet? 
Definitely gluten, one of the most evil food substance on the planet. Going on gluten free diet (be careful on high carbs consumption) may help on ataxia patients. Especially if the patient is disgnosed with Celiac disease, it is highly recommended to go on gluten free diet (ideally low to moderate carbs intake). Patients with DQ1 genes can benefit from gluten free diet. 

What tests to should I do for accurate diagnosis?
- Full battery of serological tests
- To first diagnose if the patient develop Celiac disease
- HLA (Human Leukocyte Antigen) type to be tested
- Antibodies profile (Anti GAD, TG6, TG2, anti-gliadin, endomysial)



http://www.ncbi.nlm.nih.gov/pubmed/18787912



Journals:
http://www.ncbi.nlm.nih.gov/pubmed/18787912
http://www.ncbi.nlm.nih.gov/pubmed/12566288
http://www.ncbi.nlm.nih.gov/pubmed/23860139
http://www.ncbi.nlm.nih.gov/pubmed/23576621


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